The goal of this single-center, nonrandomized, interventional non-profit pilot study is to evaluate the feasibility and clinical utility of a non-invasive near-infrared spectroscopy (NIRS) imaging device for assessing skin-flap tissue oxygen saturation in adult women undergoing mastectomy and immediate breast reconstruction after oncological surgery.
The main questions it aims to answer are:
* Can NIRS imaging provide reproducible measurements of tissue oxygen saturation (StO₂) in mastectomy skin flaps before surgery, during the intraoperative phase, and during postoperative follow-up?
* Can spatial and temporal variations in StO₂ identify areas of potentially reduced flap perfusion or impaired tissue viability?
* Can NIRS-derived oxygenation measurements support the assessment of postoperative flap healing and ischemic complications?
Participants will:
* undergo non-invasive NIRS imaging of the breast skin flap before surgery;
* undergo one intraoperative NIRS acquisition during mastectomy and immediate breast reconstruction;
* undergo repeated NIRS imaging during postoperative follow-up visits;
* receive standard surgical treatment and postoperative care according to routine clinical practice.
NIRS imaging is performed for study purposes and does not influence intraoperative surgical decision-making or the choice of reconstructive procedure.