Clinical Trial

Optimization of Respiratory Effort With Titrated Sedation in AHRF

Name: Optimization of Respiratory Effort With Titrated Sedation in AHRF — clinical trial record (NCT07679932)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: OPTIREST

Not Yet Recruiting

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Summary

Prospective, observational, monocentric study to assess the physiological effects of dexmedetomidine and remifentanil in spontaneously breathing patients with acute hypoxemic respiratory failure receiving high-flow nasal oxygen.

Trial Details

NCT Number	NCT07679932
Lead Sponsor	Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Conditions	AHRF
Enrollment	40 participants
Start Date	2026-07
Primary Completion	2028-06 (estimated)
Study Completion	2028-07 (estimated)
Updated on ClinicalTrials.gov	2026-07-01