Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 4

This study investigates the impact of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on recognition memory in healthy, regular cannabis users. Participants complete the same recognition memory task after self-administering one of two different strains of cannabis flower one day and while not intoxicated another day. Event-related potentials (ERPs) are measured via electroencephalogram (EEG) during the recognition memory task. Blood is collected to quantify THC and CBD exposure. Participants also complete self-report measures of medical history, sleep quality, subjective cognitive function, physical activity, psychological functioning, substance use, and acute drug effects.

NCT Number	NCT07679581
Lead Sponsor	L. Cinnamon Bidwell Collaborators: National Institute on Drug Abuse (NIDA)
Conditions	Cannabis, Memory, Electroencephalography
Enrollment	64 participants
Start Date	2025-12-10
Primary Completion	2027-02-01 (estimated)
Study Completion	2027-05-31 (estimated)
Updated on ClinicalTrials.gov	2026-07-01