Intraoperative Intravenous Lidocaine for Pain After Laparoscopic Appendectomy

This randomized, double-blind, placebo-controlled clinical trial evaluated whether intraoperative intravenous lidocaine infusion improves postoperative analgesia and recovery in patients undergoing laparoscopic appendectomy. The primary objective was to assess postoperative pain intensity and opioid consumption. Secondary outcomes included postoperative nausea and vomiting, time to bowel function recovery, length of hospital stay, plasma lidocaine concentrations, and adverse events.

NCT Number	NCT07678385
Lead Sponsor	Hospital Universitario de Caracas
Conditions	Post Operative Pain, Acute, Laparoscopic Appendectomy
Enrollment	225 participants
Start Date	2024-02-01
Primary Completion	2025-01-01 (estimated)
Study Completion	2025-01-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-01