Clinical Trial

Systemic Isotretinoin Therapy and Eye

Completed
View on ClinicalTrials.gov →
Summary
The dermatologist created a treatment plan for participants diagnosed with acne using medications containing vitamin A. While this medication has many benefits for the skin, it also has various side effects affecting many other systems. One of the most important of these side effects is related to the eyes. Therefore, the dermatologist will refer participants to an eye clinic for eye exams before and at regular intervals after starting this medication. During these exams, the investigators will perform eye measurements, a dry eye test, and an eye CT scan (OCTA). This study will compare patients who are scheduled to start treatment with vitamin A-containing pills for acne treatment with patients who have started treatment and completed their sixth month. This will allow for the early detection of potential side effects associated with this medication.
Trial Details
NCT Number NCT07675460
Lead Sponsor Demet Mutlu
Conditions Dry Eye, Choroidal Thickness, Retinal Vascularisation, Acne Cystic, Isotretinoin
Enrollment 60 participants
Start Date 2024-04-01
Primary Completion 2025-07-01 (estimated)
Study Completion 2025-11-01 (estimated)
Updated on ClinicalTrials.gov 2026-06-30