Endometrial Peristalsis and Pregnancy Outcomes in Hormone Replacement Therapy (HRT) - Frozen Embryo Transfer (FET) Cycles

Endometrial peristalsis may influence embryo implantation and pregnancy outcomes, but its role during hormone replacement therapy (HRT)-prepared frozen embryo transfer (FET) cycles remains unclear. This prospective observational study will assess endometrial peristalsis at predefined time points during HRT-prepared FET cycles using transvaginal ultrasonography and evaluate its association with pregnancy outcomes. The study aims to clarify the clinical significance of endometrial peristalsis in HRT-prepared FET cycles and to provide evidence supporting endometrial assessment in assisted reproductive technology.

NCT Number	NCT07675213
Lead Sponsor	Mỹ Đức Hospital
Conditions	Infertility, Endometrial Peristalsis, Uterine Contraction, Endometrial Waves, Frozen Embryo Transfer (FET), Uterine Peristalsis, Hormone Replacement Therapy (HRT)
Enrollment	442 participants
Start Date	2026-06-30
Primary Completion	2027-06-01 (estimated)
Study Completion	2027-12-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-09