Clinical Trial

GliomaAI-Astro4: MRI-Based Detection of IDH Mutant Astrocytoma Grade 4

Study acronym: GliomaAI-A4
Completed
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Summary
The goal of this observational study is to learn whether an artificial intelligence system called GliomaAI-Astro4 can help detect a specific molecular type of brain tumour called IDH mutant Astrocytoma Grade 4 using routine MRI scans. The study uses previously collected and fully anonymised MRI data from 1,372 patients from 13 institutions in the Cancer Imaging Archive (TCIA). The main questions it aims to answer are: * How accurately can GliomaAI-Astro4 identify IDH mutant Astrocytoma Grade 4 from MRI scans? * How well does the system perform across data from different hospitals and patient groups? Researchers will use existing MRI scans and clinical information to train and test the AI system. No new scans, treatments, or hospital visits are required for participants, and all data used is fully anonymised and obtained from an existing research database. Participants will not be asked to do anything, as this study only uses previously collected imaging data.
Trial Details
NCT Number NCT07673679
Lead Sponsor Deep Learning Institute of Radiological Sciences
Conditions Glioma, Glioma (Diagnosis), Astrocytoma, Astrocytoma, Grade IV, Astrocytoma, IDH-Mutant, Grade 4
Enrollment 1,372 participants
Start Date 2017-03-14
Primary Completion 2021-03-09 (estimated)
Study Completion 2021-06-16 (estimated)
Updated on ClinicalTrials.gov 2026-06-29