Incidence of Chronic Pain in Patients Undergoing Knee Arthroplasty Within a Fast-Track Protocol

The goal of this study is to learn about pain after knee replacement surgery. The surgery uses a fast-recovery program called Enhanced Recovery After Surgery (ERAS). The main questions are: How many participants still have pain three months after surgery? How severe is the pain? How many participants still use strong pain medication (opioids)? Participants are adults undergoing knee replacement surgery at UZ Gent and following the ERAS program. Researchers will collect information on pain and recovery before surgery and for up to three months afterward. Participants will answer simple questions about their pain and daily activities. This study will help researchers understand post-surgical recovery and may help improve pain care in the future.

NCT Number	NCT07673276
Lead Sponsor	University Hospital, Ghent
Conditions	Chronic Post Surgical Pain, Functional Recovery, ERAS, Chronic Opioid Use, Inthrathecal Morfine, Knee Arthroplasty
Enrollment	153 participants
Start Date	2025-02-24
Primary Completion	2026-07-01 (estimated)
Study Completion	2026-07-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-29