Clinical Trial

Omega-3 Plus Low-Dose Aspirin in Smokers With Stage III Periodontitis

Study acronym: OASP
Recruiting
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Record status
This record was last updated July 8, 2026 (before its estimated July 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
This randomized double-blind placebo-controlled clinical trial aims to evaluate the clinical and biochemical effects of omega-3 fatty acids combined with low-dose aspirin as an adjunct to scaling and root planing (SRP) in smoker patients with Stage III periodontitis. The study compares test and control groups regarding periodontal clinical parameters and gingival crevicular fluid interleukin-1 beta (IL-1β) levels Or other inflammatory markers that will be determined later at baseline, 3 months, and 6 months following treatment
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-06-23.
Trial Details
NCT Number NCT07673185
Lead Sponsor Al-Azhar University
Conditions Periodontal Disease, Periodontitis (Stage 3), Smoking Behaviors
Enrollment 40 participants
Start Date 2025-01-15
Primary Completion 2026-07-30 (estimated)
Study Completion 2026-10-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-08