Clinical Trial

Comparison of Er-YAG Laser, Air Polishing, and Surgical Excision for Gingival Hyperpigmentation

Study acronym: APGH
Completed
View on ClinicalTrials.gov →
Summary
This randomized controlled clinical trial aimed to compare the effectiveness of different treatment approaches for physiologic gingival hyperpigmentation. Participants with gingival melanin pigmentation were randomly assigned to one of four treatment groups: Er:YAG laser treatment, air polishing with erythritol powder, air polishing with sodium bicarbonate powder, or conventional surgical excision. Clinical outcomes were evaluated using pigmentation index scores, digital image analysis, and color measurements at baseline and follow-up visits. Patient-centered outcomes, including postoperative discomfort and satisfaction, were also assessed. The study sought to determine whether air polishing techniques could provide clinical outcomes comparable to conventional treatment approaches while improving patient comfort and satisfaction.
Trial Details
NCT Number NCT07672587
Lead Sponsor Ondokuz Mayıs University
Conditions Gingival Hyperpigmentation, Oral Pigmentation
Enrollment 24 participants
Start Date 2025-12-01
Primary Completion 2026-06-01 (estimated)
Study Completion 2026-06-01 (estimated)
Updated on ClinicalTrials.gov 2026-06-29