Clinical Trial

VA Consolidation in Intermediate-Risk AML

Recruiting Phase 2
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Summary
This clinical trial aims to compare the efficacy and safety of venetoclax-based consolidation therapy versus conventional consolidation chemotherapy (intermediate/high-dose cytarabine) in newly diagnosed adult patients with intermediate-risk acute myeloid leukemia (AML). Participants must have achieved complete remission (CR) or CR with incomplete hematologic recovery (CRi) after induction therapy with venetoclax and azacitidine and are planned to undergo allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Trial Details
NCT Number NCT07672262
Lead Sponsor The First Affiliated Hospital of Soochow University
Conditions Acute Myeloid Leukemia, Intermediate Risk Acute Myeloid Leukemia, Consolidation Therapy
Enrollment 226 participants
Start Date 2026-06-01
Primary Completion 2030-06-01 (estimated)
Study Completion 2030-06-01 (estimated)
Updated on ClinicalTrials.gov 2026-08-06