Clinical Trial

Angiotensin II for Post Cardiac Surgery Vasoplegia (ANGII_V)

Study acronym: ANGII_V
Not Yet Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
The goal of this study is to conduct a prospective trial implementing a modified version of the Emory Protocol for administering ANG II to patients with post cardiac bypass vasoplegia. The main questions we aim to answer are: 1.) does administration of improve mortality, 2.) does the administration of Ang II using the modified protocol shorten the time needed to reach optimal MAP, 3.) does the administration of Ang II using the modified protocol shorten length of stay in the ICU and hospital? Researchers will compare outcomes from the interventional group to historical controls who did not receive Ang II using the modified protocol.
Trial Details
NCT Number NCT07671365
Lead Sponsor Methodist Healthcare System of San Antonio
Conditions Vasoplegic Shock, Cardiopulmonary Bypass, Vasoplegia
Enrollment 329 participants
Start Date 2026-07
Primary Completion 2029-07 (estimated)
Study Completion 2030-08 (estimated)
Updated on ClinicalTrials.gov 2026-06-26