Comparing Digital and Collaborative Gamified Reinforcement Strategies for HPV Literacy and Retention Among Nursing Students

This randomized comparative study aims to evaluate the effectiveness of two gamified reinforcement strategies, Gimkit and Escape Room, on human papillomavirus (HPV) literacy, short-term retention, and gameful learning experiences among undergraduate nursing students. Following standardized theoretical instruction on HPV infection, participants will be randomly assigned to either a digital quiz-based gamification intervention (Gimkit) or a collaborative Escape Room activity. Outcomes will be assessed using the Human Papillomavirus Literacy Scale (HPV-LS) and the Gameful Experience Scale (GAMEX) at multiple time points, including baseline, post-theoretical instruction, post-intervention, and one-month follow-up.

NCT Number	NCT07667127
Lead Sponsor	Aydin Adnan Menderes University
Conditions	Health Literacy, Human Papillomavirus (HPV) Infection, Nursing Education
Enrollment	64 participants
Start Date	2026-09-21
Primary Completion	2026-10-26 (estimated)
Study Completion	2026-10-26 (estimated)
Updated on ClinicalTrials.gov	2026-07-02