Using Sensorimotor Reorganization Following Upper Limb Amputation to Improve Prosthetic Control

Amputation of an upper limb results in a disruption of the sensorimotor loop and a reorganization of the nervous system, leading to the emergence of a phantom limb and the adaptation of compensatory motor strategies. This project aims to leverage these phenomena (induced sensations, phantom mobility, and compensations) to improve control, sensory feedback, and the appropriation of prostheses, in order to reduce cognitive load and musculoskeletal disorders.

NCT Number	NCT07666204
Lead Sponsor	Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est Collaborators: Institut des Sciences du Mouvement, Institut des Systèmes Intelligents et de Robotique, Laboratoire des Sciences du Numérique de Nantes, Institut de Recherche en Informatique et Systèmes Aléatoires
Conditions	Amputation of Upper Limb, Agenesis of Upper Limb
Enrollment	50 participants
Start Date	2026-04-15
Primary Completion	2030-04-30 (estimated)
Study Completion	2030-04-30 (estimated)
Updated on ClinicalTrials.gov	2026-06-24