JUgular Gating for Upright Level Adjustment and Targeted Enhancement of Cerebral Perfusion

Investigators aim to demonstrate that the evolution of intracranial pressure (ICP) is nonlinear and may be influenced by jugular vein collapse. This collapse is estimated to occur at the angle where the hydrostatic pressure of the blood column matches the central venous pressure, and it can be assessed using ultrasonography. This approach allows for the determination of an individualized tilt angle, optimizing cerebral perfusion pressure without compromising venous drainage.

NCT Number	NCT07665606
Lead Sponsor	University Hospital, Bordeaux
Conditions	Intracranial Pressure, Critical Care
Enrollment	30 participants
Start Date	2026-09-01
Primary Completion	2027-03-31 (estimated)
Study Completion	2027-03-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-24