Metabolic Reprogramming and Microenvironment in Pancreatic Adenocarcinoma

The present project aims to elucidate the metabolic interactions within the tumor microenvironment of pancreatic adenocarcinoma, both in the primary tumor and in hepatic and pulmonary metastatic sites, as well as in circulating blood biomarkers. Deciphering these complex interactions aims to identify exploitable vulnerabilities for predicting treatment efficacy or for guiding therapeutic strategies.

NCT Number	NCT07664891
Lead Sponsor	Institut Paoli-Calmettes
Conditions	Pancreatic Adenocarcinoma Metastatic
Enrollment	64 participants
Start Date	2025-09-11
Primary Completion	2028-09-01 (estimated)
Study Completion	2028-09-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-24