Clinical Trial

Comparison of Digital Analysis and Artificial Intelligence for Cephalometric Tracing

Recruiting
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Summary
This study aims to evaluate the accuracy and reliability of artificial intelligence (AI)-based cephalometric analysis compared with digital manual tracing. A total of 100 standardized lateral cephalometric radiographs will be analyzed using Delta-Dent software with manual landmark identification and three fully automated AI-based systems (WebCeph, QuantX, and Smartee). Sagittal, vertical, dental, and soft tissue cephalometric parameters will be compared among the different methods. Statistical analysis will assess inter-method agreement and the clinical relevance of any observed discrepancies. The study seeks to determine whether AI-based systems provide measurements comparable to conventional digital tracing and whether they can be considered reliable adjunctive tools in orthodontic diagnosis and treatment planning.
Trial Details
NCT Number NCT07664488
Lead Sponsor University of Pavia
Conditions Cephalometric Analysis, Cephalometry, Artificial Intelligence (AI), Artificial Intelligence (AI) in Diagnosis
Enrollment 100 participants
Start Date 2026-06-01
Primary Completion 2026-09-30 (estimated)
Study Completion 2026-09-30 (estimated)
Updated on ClinicalTrials.gov 2026-06-24