Effects of Magnesium and Spinning Training on Echocardiographic, Inflammatory, and Aerobic Outcomes

Regular aerobic exercise may improve cardiorespiratory fitness while modulating systemic inflammation and oxidative stress. Spinning, as a structured indoor cycling modality, provides a practical aerobic exercise model with adjustable intensity and duration, but its effects on redox balance, inflammatory status, aerobic capacity, and cardiac functional parameters may vary according to individual recovery and nutritional status. Magnesium is an essential micronutrient involved in energy metabolism, muscle contraction-relaxation, ion regulation, and inflammatory and oxidative pathways; therefore, magnesium use may be relevant to exercise adaptation and recovery. This study aims to evaluate the associations of magnesium use and spinning training with oxidative stress, inflammation, aerobic capacity, and cardiac parameters. In this context, biochemical markers related to oxidative/antioxidant status and inflammation, aerobic performance indicators, and echocardiographic cardiac function parameters will be assessed together. The study is expected to provide real-world evidence on whether magnesium use in individuals participating in spinning training is associated with more favorable redox, inflammatory, aerobic, and cardiac profiles.

NCT Number	NCT07662954
Lead Sponsor	Karamanoğlu Mehmetbey University
Conditions	Oxidative Stress, Inflammation, Physical Fitness, Echocardiography, Exercise, Healthy Volunteers
Enrollment	48 participants
Start Date	2026-06-01
Primary Completion	2026-08-15 (estimated)
Study Completion	2026-08-20 (estimated)
Updated on ClinicalTrials.gov	2026-06-23