Clinical Trial

CD45RA-depleted DLI for the Treatment of Refractory/Persistent Viral Infections After Haploidentical Transplantation

Study acronym: CD45RADLITx
Recruiting Phase 1/2
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Summary
The goal of this clinical trial is to learn whether giving patients special donor immune cells (called "CD45RA Depleted DLI") can help treat viral infections that have not improved with standard antiviral drugs. These infections occur after a stem cell transplant. The study will also look at the safety of this treatment.
Trial Details
NCT Number NCT07662369
Lead Sponsor Ruijin Hospital
Collaborators: Shanghai Liquan Hospital
Conditions Hematologic Malignancy, Haplo-identical HCT
Enrollment 30 participants
Start Date 2026-06-01
Primary Completion 2027-06-30 (estimated)
Study Completion 2028-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-06-23