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Taste Acceptance and Effectiveness of Hyaluronic Acid and Chlorhexidine Mouthwashes in Children With Gingivitis

StatusNot Yet Recruiting
PhasePhase 1
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 4 months later Nov 30, 2026 → Apr 1, 2027
Primary endpoint reworded 1 of 1 changed
Enrollment reduced 25% 32 → 24 participants
See other at-risk trials from Cairo University

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary endpoint(s) modified Show 7 more changesShow less
    • Start date: Aug 1, 2026 to Jan 1, 2027
    • Primary completion pushed from Nov 30, 2026 to Apr 1, 2027
    • Enrollment reduced: 32 → 24 participants
    • Study completion pushed from May 1, 2027 to Jul 1, 2027
    • Eligibility criteria expanded, about 10 words
    • Secondary endpoints revised (2)
    • Study description expanded, about 1 word
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Cairo University
1,562 trials monitored
See 18 trials at risk
This randomized controlled clinical trial aims to compare the taste acceptance and clinical effectiveness of hyaluronic mouthwash and chlorhexidine mouthwash in children with plaque-induced gingivitis. Clinical outcomes will be assessed using gingival and plaque indices, while taste acceptance will be evaluated using a validated hedonic scale. The findings may help identify a mouthwash that is both effective and acceptable to children, thereby improving adherence to oral hygiene practices.
Trial Details
NCT Number NCT07662226
Lead Sponsor Cairo University
Conditions
(from sponsor)		 Plaque Induced Gingival Disease
Related terms Gingivitis
Enrollment 24 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov