Deep Margin Elevation in Endodontically Treated Posterior Teeth

This study aims to evaluate the periodontal response of proximal surfaces with deep margin elevation (DME) in endodontically treated posterior teeth restored with CAD/CAM systems. Deep subgingival margins present clinical challenges in terms of isolation, restoration, and long-term periodontal health. DME is a minimally invasive technique used to relocate subgingival margins coronally to a supragingival level, facilitating adhesive procedures and CAD/CAM restoration placement. However, the periodontal effects of DME remain unclear. In this prospective split-tooth clinical study, proximal surfaces treated with DME will be compared with control surfaces without DME within the same tooth. The primary outcome will be bleeding on probing (BOP), while secondary outcomes will include probing depth and plaque index. Clinical and radiographic evaluations will be performed at baseline and during follow-up. The results of this study are expected to provide clinical evidence regarding the periodontal impact of DME and support clinical decision-making in the restoration of endodontically treated posterior teeth.

NCT Number	NCT07661719
Lead Sponsor	Hacettepe University
Conditions	Periodontal Health, Endodontically Treated Teeth
Enrollment	45 participants
Start Date	2026-03-24
Primary Completion	2026-10-24 (estimated)
Study Completion	2027-04-24 (estimated)
Updated on ClinicalTrials.gov	2026-07-02