High-Intensity Laser Therapy (HILT) in Patients With Knee Osteoarthritis

This randomized placebo-controlled trial aims to evaluate the effectiveness of High-Intensity Laser Therapy (HILT) as an adjunct to standard outpatient physiotherapy in patients with knee osteoarthritis. Seventy-two participants will be randomly assigned to receive either conventional physiotherapy combined with active HILT or conventional physiotherapy combined with sham HILT. Outcomes related to pain, knee function, physical performance, muscle strength, range of motion, psychosocial factors, quality of life and body composition will be assessed at baseline, after the intervention, and at 8-week follow-up.

NCT Number	NCT07661407
Lead Sponsor	University of Rzeszow
Conditions	Knee Osteoarthritis (Knee OA)
Enrollment	72 participants
Start Date	2026-07-03
Primary Completion	2027-02-28 (estimated)
Study Completion	2028-03-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-29