The Impact of Initiating Dotinurad Urate-Lowering Therapy at Different Time Windows on Gout Flare Resolution Time

To confirm that initiating Dotinurad for uric acid uric acid lowering during the acute phase of gout is non-inferior to initiating it after the acute phase of gout has subsided, and to analyze whether initiating Dotinurad treatment during the acute phase will increase the pain level, the recurrence rate of gout, and the inflammatory level of patients.

NCT Number	NCT07661030
Lead Sponsor	First Affiliated Hospital of Wenzhou Medical University Collaborators: The Affiliated People's Hospital of Ningbo University, Wenzhou Central Hospital, Yuyao People's Hospital
Conditions	Gout
Enrollment	142 participants
Start Date	2026-07-30
Primary Completion	2027-07-30 (estimated)
Study Completion	2027-07-30 (estimated)
Updated on ClinicalTrials.gov	2026-06-22