Clinical Trial

A Clinical Study of X-Clip Mitral Valve Clip System and Steerable Guide System for Transcatheter Mitral Valve Repair of Degenerative Mitral Regurgitation

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Summary
Shenzhen Lifevalve Medical Scientific Co., Ltd. has developed a new X-Clip Mitral Valve Clip System and its compatible Steerable Guide System, aiming to provide transcatheter mitral valve repair for patients with degenerative mitral regurgitation. The two systems have completed all preclinical tests, including design verification tests, biological evaluation, and animal studies. All the test results confirmed that the systems met relevant design requirements. A First-in-Man clinical study was conducted in China in 2023, involving 11 patients. The study provides initial evidence that the X-Clip Mitral Valve Clip System and Steerable Guide System demonstrate favourable safety and efficacy in the treatment of mitral regurgitation in the Chinese population. The device is currently undergoing a pivotal clinical trial in China. This study is a clinical study aimed to evaluate the safety and performance of the X-Clip Mitral Valve Clip System and Steerable Guide System in European population.
Trial Details
NCT Number NCT07660185
Lead Sponsor Shenzhen Lifevalve Medical Scientific Co., Ltd.
Collaborators: Lifetech Scientific (Shenzhen) Co., Ltd.
Conditions Transcatheter Mitral Valve Repair of Degenerative Mitral Regurgitation
Enrollment 15 participants
Start Date 2027-03-01
Primary Completion 2028-05-31 (estimated)
Study Completion 2032-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-22