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Effects of Acetyl L-Carnitine Supplementation on Clinical, Metabolic and Inflammatory Symptoms in Obese, Diabetic, Postmenopausal Women With Osteoarthritis

StatusCompleted
PhaseNot applicable
Started
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Record History

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  1. Primary endpoint(s) modified Show 7 more changesShow less
    • Start date: Nov 1, 2025 to Dec 1, 2025
    • Trial completed
    • Primary completion date changed from estimate of Jul 30, 2026 to Jul 15, 2026
    • Study completion date changed from estimate of Aug 30, 2026 to Aug 15, 2026
    • Eligibility criteria expanded, about 12 words
    • Secondary endpoint revised
    • Publications: details revised at 6 of 6 entries
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
OA is a degenerative bone disease more common in postmenopausal women. Diabetes and obesity are common risk factors for the development of OA. The common symptoms include pain and disability of the affected joint, leading to mobility issues. Acetyl L-carnitine due to its known anti-inflammatory, chondroprotective, and improved insulin-sensitizing effects may help in alleviating the symptoms and progression of OA in obese diabetic postmenopausal women.
Trial Details
NCT Number NCT07660081
Lead Sponsor Khyber Medical University Peshawar
Conditions
(from sponsor)		 Osteoarthritis, Type 2 Diabetes, Obesity
Related terms Diabetes Mellitus, Type 2, Obesity, Osteoarthritis
Enrollment 100 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov