This study aims to develop and evaluate a peer-led training program specifically designed for Nurse Practitioners (NPs) to acquire Point-of-Care Ultrasound (POCUS) skills. POCUS, known for its non-invasive nature and real-time imaging capability, has been widely applied in clinical fluid status assessment and plays a pivotal role in enhancing diagnostic efficiency and quality of care. However, current POCUS training resources for NPs in Taiwan remain insufficient, limiting their clinical application and professional visibility. Using a quasi-experimental design, this study investigates the effectiveness of peer-led instruction in strengthening image interpretation, clinical reasoning, and self-efficacy among NPs. The ultimate goal is to establish an evidence-based, nursing-oriented POCUS education model to fill existing gaps in the training system and elevate the role of NPs in multidisciplinary care.