Fospropofol Disodium Versus Propofol for Patient Satisfaction in Ureteroscopy

This single-center single-blind randomized trial compares fospropofol disodium and propofol for anesthesia in elective ureteroscopy patients. A total of 190 eligible adults will be randomly divided into two groups at 1:1 ratio with identical intraoperative maintenance protocols. The primary outcome is 24-hour postoperative anesthesia satisfaction assessed by ISAS scale; secondary and safety endpoints include injection pain, intraoperative hemodynamic events and various perioperative adverse reactions. This study explores the clinical efficacy and safety of the two sedatives to guide rational clinical medication.

NCT Number	NCT07659132
Lead Sponsor	Shiyou Wei
Conditions	Anesthesia for Urologic Endoscopic Surgery, Urinary Calculi
Enrollment	190 participants
Start Date	2026-06-26
Primary Completion	2026-09-25 (estimated)
Study Completion	2026-09-26 (estimated)
Updated on ClinicalTrials.gov	2026-06-24