Daily Versus Alternate-Day Oral Iron Therapy for Anemia in Second-Trimester Pregnancy

This randomized controlled trial compares daily versus alternate-day oral iron supplementation in pregnant women with iron deficiency anemia during the second trimester. The study evaluates changes in hemoglobin and serum ferritin, treatment adherence, and gastrointestinal side effects to inform more patient-centered, physiologically aligned dosing strategies.

NCT Number	NCT07657455
Lead Sponsor	Pakistan Air Force (PAF) Hospital Islamabad
Conditions	Iron Deficiency Anemia, Anemia in Pregnancy
Enrollment	184 participants
Start Date	2026-09
Primary Completion	2026-12 (estimated)
Study Completion	2027-02 (estimated)
Updated on ClinicalTrials.gov	2026-06-18