Assessment of Bone Density Following Application of BMAC Around Zygomatic Implant

This prospective case series is designed to evaluate the effect of autologous bone marrow aspirate concentrate applied around zygomatic implants placed via the intrasinus approach. The study will include adult patients with severe maxillary atrophy requiring zygomatic implant rehabilitation. BMAC will be prepared from iliac crest aspirate and loaded on gelatin sponge at the implant site. Peri-implant bone density will be assessed using CBCT at baseline and 6 months postoperatively. Secondary implant stability will be measured using resonance frequency analysis. (Recruitment has not started yet)

NCT Number	NCT07657026
Lead Sponsor	Cairo University
Conditions	Severe Maxillary Atrophy
Enrollment	10 participants
Start Date	2026-06-15
Primary Completion	2027-04-15 (estimated)
Study Completion	2027-06-15 (estimated)
Updated on ClinicalTrials.gov	2026-06-30