Clinical Trial

Continuous Infusion Versus Intermittent IV Bolus of Cefazolin: Prevention of Surgical Site Infection During Orthopedic Surgeries in Egyptian Patients.

Not Yet Recruiting Phase 4
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Summary
A randomized controlled trial on adults who underwent orthopedic surgery. To evaluate the effectiveness of intraoperative continuous infusion (CI) of cefazolin compared with intermittent (INT) cefazolin administration in preventing SSIs in the orthopedic surgical population. Eligible patients will be randomized in a block design into 2 groups: intervention and control. The intervention group will use continuous infusion of cefazolin (CI), while the control group will follow the traditional presurgical prophylaxis protocol of intermittent cefazolin doses (INT).
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-06-13.
Trial Details
NCT Number NCT07655596
Lead Sponsor Helwan University
Conditions Surgical Site Infection (SSI)
Enrollment 100 participants
Start Date 2026-07-01
Primary Completion 2026-09-30 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-24