Clinical Trial

Rapid Microaxial Flow Pump Support and Escalation in Patients With Myocardial Infarction Associated Cardiogenic Shock and Persistent Need of Hemodynamic Support

Study acronym: RISE
Recruiting
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Summary
The aim of this trial is to evaluate whether a structured and time-optimized escalation strategy from a transfemoral microaxial flow-pump (Impella CP™) to the Impella 5.5™ microaxial flow-pump is associated with improved clinical outcomes and fewer adverse events in patients with cardiogenic shock due to acute myocardial infarction
Protocol Amendment History 1 change
critical Recruitment opened 2026-06-25
Trial Details
NCT Number NCT07655479
Lead Sponsor University Hospital of Cologne
Collaborators: Johnson & Johnson
Conditions Cardiogenic Shock Post Myocardial Infarction
Enrollment 115 participants
Start Date 2026-04-23
Primary Completion 2028-10 (estimated)
Study Completion 2028-10 (estimated)
Updated on ClinicalTrials.gov 2026-06-24