Active and Mindful - A Mind-Body Programme for People With Multiple Sclerosis: a Feasibility Study Protocol

The purpose of this exploratory study is to evaluate the feasibility and acceptability of the "Active and Mindful" home-based mind-body exercise program for individuals diagnosed with Multiple Sclerosis (MS) in Portugal and Spain. Multiple Sclerosis often leads to physical and psychological challenges that impact health-related quality of life. Mind-body exercise programs combined with remote supervision present an accessible, flexible alternative to traditional center-based rehabilitation. This study assesses the practicality of implementing a 9-month online intervention delivered via video-conferencing, focusing on recruitment rates, retention, participant attendance, and overall satisfaction. Secondarily, the study explores pre-to-post changes in clinical and psychological indicators such as perceived physical exertion and health-related quality of life.

NCT Number	NCT07654699
Lead Sponsor	Catarina Alexandra Nunes Martins Collaborators: University of Évora, Comprehensive Health Research Center, Sociedade Portuguesa de Esclerose Múltipla, Asociación de Familiares y Afectados de Esclerosis Múltiple
Conditions	Multiple Sclerosis
Enrollment	50 participants
Start Date	2024-03-01
Primary Completion	2025-04-01 (estimated)
Study Completion	2025-04-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-29