This randomized controlled study aims to evaluate the effectiveness of virtual reality simulator-based training in teaching the inferior alveolar nerve block (IANB) technique to third-year dental students. Participants were randomly assigned to either a virtual reality simulator training group or a conventional training group. The outcomes evaluated include theoretical knowledge, anatomical understanding, procedural performance, self-confidence, and anxiety levels associated with IANB administration. The study aims to determine whether virtual reality simulation provides advantages over conventional educational methods in local anesthesia training.