Music Therapy for Oral Mucositis Pain in Pediatric Patients

This mixed-methods pilot study will examine the effect of music therapy on oral mucositis pain in pediatric oncology patients. Oral mucositis, characterized by painful ulcerative lesions in the mouth, is a common side effect of high-dose chemotherapy and hematopoietic stem cell or bone marrow transplantation. Despite its high prevalence and impact on quality of life, effective pain management strategies for pediatric oral mucositis remain limited and often rely heavily on medications that may cause significant side effects or provide insufficient relief. Music therapy may offer a promising non-pharmacologic adjunct for reducing pain, yet no studies to date have specifically evaluated its use for oral mucositis pain in pediatric patients.

NCT Number	NCT07653360
Lead Sponsor	University of California, San Francisco Collaborators: Perloff Family Foundation
Conditions	Oral Mucosa Discomfort, Pediatric Cancer, Mucositis Oral
Enrollment	50 participants
Start Date	2026-07-01
Primary Completion	2027-05-31 (estimated)
Study Completion	2027-05-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-17