Clinical Trial

Clinical Characteristics of Recompensation

Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
Recompensation in decompensated liver cirrhosis is an emerging clinical endpoint; however, standardized criteria and long-term prognostic data are currently lacking. This retrospective study aims to address these gaps by analyzing a cohort of patients with HBV-related and alcohol-related cirrhosis. This retrospective cohort study aims to validate established recompensation criteria and propose new standards for defining stable liver function. Additionally, the study will characterize the natural history of recompensated patients by tracking the duration of recompensation, incidence of hepatocellular carcinoma, and liver-related mortality. Statistical analysis will be performed to identify baseline predictors for achieving recompensation and to determine risk factors for subsequent re-decompensation events. Identify Predictors: Analyze baseline characteristics to identify independent predictors for achieving recompensation. Evaluate Risks: Investigate risk factors associated with re-decompensation in patients who have successfully achieved recompensation.
Trial Details
NCT Number NCT07651683
Lead Sponsor Third Affiliated Hospital, Sun Yat-Sen University
Conditions Cirrhosis, Alcohol Related Liver Disease, HBV (Hepatitis B Virus), Recompensation
Enrollment 300 participants
Start Date 2026-03-31
Primary Completion 2027-03-01 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-16