Clinical Trial

Comparison Immune Response in Paravertebral and Erector Spinal Plane Block in Breast Cancer Patients

Study acronym: IRPVBESP
Not Yet Recruiting
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Summary
The goal of this clinical trial is to find the difference in immune response between two types of regional anesthesia in female patients suffering from breast cancer. The main question it aims to answer is there a difference in the immune response between paravertebral block and erector spinal plane block. Hypothresis of the study is that paravertebral block with propofol induces less immune response in surgical treatment of breast cancer patients than erector spinal plane block. Participants will be asked to sign the informant consent. They will be given either paravertebral block or erector spinae plane block with general anesthesia using propofol. Their venous blood will be taken 1 hour prior surgery and 24 and 48 hours after surgery.
Trial Details
NCT Number NCT07648810
Lead Sponsor Clinical Hospital Center Rijeka
Conditions Breast Cancer - Female
Enrollment 56 participants
Start Date 2026-06-15
Primary Completion 2026-10-15 (estimated)
Study Completion 2027-04-15 (estimated)
Updated on ClinicalTrials.gov 2026-06-15