Clinical Performance of CAD/CAM Hard Hybrid Ceramic Inlays Versus Resin Composite Inlays in Vital Molars With Extensive Occluso-Proximal Cavities

this study aims to compare the clinical performance of hard hybrid ceramics and composite resin indirect restorations fabricated by CAD/CAM technology for the vital teeth with occluso-proximal cavities. the clinical performance assessed include marginal adaptation primarily and in addition to Color match, marginal discoloration, aesthetic anatomic form, recurrent caries and restoration fracture and post-operative hypersensitivity. the clinical performance will be assessed after the restoration cementation, after 6, 12, 18 and 24 months.

NCT Number	NCT07648485
Lead Sponsor	Cairo University
Conditions	Dental Caries, Cavity, Dental, Proximal Dental Caries
Enrollment	50 participants
Start Date	2026-08
Primary Completion	2028-08 (estimated)
Study Completion	2028-11 (estimated)
Updated on ClinicalTrials.gov	2026-06-16