Therapy Adjustment and IndividuaLized Response With Biomarker Observation in ReaL-world Heart Failure

The goal of TAILOR-HF is to integrate clinical data, laboratory parameters, treatment patterns, and circulating biomarkers to identify factors that predict individual response to pharmacological treatment in patients with heart failure. TAILOR-HF is an observational study with protocol-mandated assessments scheduled at baseline and at 1, 3, and 6 months after enrolment. Additional follow-up data will be collected through telephone visits every 6 months until the last participant has completed the protocol-mandated 6-month visit.

NCT Number	NCT07647848
Lead Sponsor	Maastricht University Medical Center Collaborators: UMCG, University Hospital (Groningen, The Netherlands), Leiden University Medical Center, Erasmus Medical Center, Uniklinik RTWH Aachen, Charite University, Berlin, Germany, Ospedale San Donato, Fidenza Hospital, Desio Hospital, Gorizia Hospital, UZ Antwerpen, Medizinischen Universität Wien, University College Dublin, University of Ulster, University of Glasgow
Conditions	Chronic Heart Failure, Acute Decompensated Heart Failure
Enrollment	600 participants
Start Date	2026-09-01
Primary Completion	2028-09-01 (estimated)
Study Completion	2028-09-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-15