Clinical Trial

Connective Tissue Massage and Music-Based Progressive Muscle Relaxation in Primary Dysmenorrhea

Recruiting
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Summary
This randomized controlled clinical trial aims to investigate the effects of Connective Tissue Massage (CTM) and music-based Progressive Muscle Relaxation Training (PMRT) on pain intensity, pressure pain threshold, analgesic use, and menstruation-related symptoms in women with primary dysmenorrhea. Participants will be randomly assigned to one of three groups: CTM, music-based PMRT, or control. Baseline assessment will be conducted during menstrual days 1-2 of Cycle 0. The interventions will be applied during the premenstrual intervention window of Cycle 0, from the estimated ovulation day, calculated as cycle length minus 14 days, until Cycle 1 Day 1. Post-intervention assessment will be conducted during menstrual days 1-2 of Cycle 1. No intervention will be applied after the post-intervention assessment, and follow-up assessment will be conducted during menstrual days 1-2 of Cycle 2. Outcomes including pain intensity, pressure pain threshold, analgesic use, menstrual symptoms, attitudes toward menstruation, functional and emotional impact of dysmenorrhea, and pain catastrophizing will be evaluated across menstrual cycles. Participant satisfaction and adherence to the interventions will also be assessed.
Protocol Amendment History 5 changes
critical Recruitment opened 2026-07-01
minor Completion moved earlier: 2026-12-30 -> 2026-11-15 2026-07-01
critical Primary endpoint(s) modified 2026-06-25
notable Primary completion moved earlier: 2027-03 -> 2026-11-15 2026-06-25
minor Completion moved earlier: 2028-06 -> 2026-12-30 2026-06-25
Trial Details
NCT Number NCT07647276
Lead Sponsor Pamukkale University
Collaborators: The Scientific and Technological Research Council of Turkey
Conditions Primary Dysmenorrhea
Enrollment 36 participants
Start Date 2026-06-22
Primary Completion 2026-10-30 (estimated)
Study Completion 2026-11-15 (estimated)
Updated on ClinicalTrials.gov 2026-06-30