Closed Loop Glucose Control in a Simulated ICU Setting

This is a proof of concept safety study of a rule-based closed loop glucose control system designed for use in the intensive care unit setting. The persons with type 1 and type 2 diabetes in this study will have their glucose controlled to a range of 100-140 mg/dL by a fully autonomous novel rule-based closed loop glucose control system for a period of 24 hours. The subjects will consume three standardized meals and receive a continuous intravenous infusion of dextrose (D-glucose) during the 24 hour study period. Meals will not be announced to the glucose control system.

NCT Number	NCT07646067
Lead Sponsor	Ideal Medical Technologies Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Emory University
Conditions	Type 1 Diabetes, Type 2 Diabetes, Stress Induced Hyperglycemia
Enrollment	6 participants
Start Date	2026-07
Primary Completion	2026-12 (estimated)
Study Completion	2027-12 (estimated)
Updated on ClinicalTrials.gov	2026-06-12