Trans-nasal Sphenopalatine Ganglion Block for Prevention of Emergence Agitation Following Functional Endoscopic Sinus Surgery

This randomized double-blind controlled trial aims to evaluate whether bilateral trans-nasal sphenopalatine ganglion block (SPGB) using bupivacaine reduces the incidence of emergence agitation following Functional Endoscopic Sinus Surgery (FESS) compared with placebo. Secondary objectives include evaluation of postoperative pain, postoperative opioid consumption, hemodynamic parameters, postoperative nausea and vomiting, and adverse events.

NCT Number	NCT07645521
Lead Sponsor	Mansoura University
Conditions	Chronic Rhinosinusitis (CRS), Emergence Agitation
Enrollment	100 participants
Start Date	2025-01-05
Primary Completion	2026-02-07 (estimated)
Study Completion	2026-04-13 (estimated)
Updated on ClinicalTrials.gov	2026-06-12