Clinical Trial

Efficacy and Safety of a Topical Botanical Extract Formulation for Skin Barrier Repair

Active, Not Recruiting
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Summary
This is a single-center, double-blinded, placebo-controlled, prospective clinical study designed to evaluate the skin barrier repair efficacy and local tolerance of topical cosmetic formulations containing a botanical extract. Skin barrier challenge is induced via standardized tape stripping on the volar forearm of healthy subjects. The study will evaluate and compare the repair kinetics of two concentrations of the active formulation, a vehicle, and an untreated control zone over a 14-day application period.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-06-09.
Trial Details
NCT Number NCT07645339
Lead Sponsor L'Oreal
Conditions Impaired Barrier
Enrollment 35 participants
Start Date 2025-10-13
Primary Completion 2025-11-03 (estimated)
Study Completion 2026-07-25 (estimated)
Updated on ClinicalTrials.gov 2026-06-16