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The Effects of Different Anesthetics on the Brain's Neural Networks

StatusNot Yet Recruiting
PhasePhase 4
Started2026-06-09
View on ClinicalTrials.gov ↗
Record status
This record was last updated June 12, 2026 (before its estimated August 31, 2026 completion). Its status may not reflect the trial's current state.
624 trials monitored
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This study aims to analyze the electroencephalographic power spectrum and connectivity during unresponsive states induced by propofol, esketamine and dexmedetomidine, respectively. It intends to explore the macro neural mechanisms underlying anesthetic unresponsiveness, so as to further elucidate the mechanisms by which anesthetics induce loss and recovery of consciousness. In addition, this study will identify neural biomarkers under general anesthesia for monitoring patients' actual intraoperative consciousness status. The findings will facilitate the development of monitoring indicators and devices reflecting intraoperative consciousness during general anesthesia, enabling more accurate assessment of patients' intraoperative consciousness status.
Trial Details
NCT Number NCT07644663
Lead Sponsor Fudan University
Conditions Electroencephalogram (EEG), Anesthesia
Enrollment 120 participants
Start Date 2026-06-09
Primary Completion 2026-08-31 (estimated)
Study Completion 2026-09-10 (estimated)
Updated on ClinicalTrials.gov 2026-06-12