Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia

The goal of this interventional study is to learn whether noninvasive brain stimulation (NIBS) will have an effect on pain perception in people with fibromyalgia. The main questions it aims to answer are: Do repeated sessions of NIBS lead to a reduction in perceived pain? Do repeated sessions of NIBS lead to an improvement in quality of life? Researchers will compare different brain targets to see if effects are different between them. Participants will receive repeated daily sessions of NIBS over 4 weeks with application of pressure pain algometry, and complete various questionnaires.

NCT Number	NCT07644221
Lead Sponsor	Pulkit Grover Collaborators: Department of Anesthesiology & Perioperative Medicine, University of Pittsburgh, University of Pittsburgh Clinical and Translational Science Institute (CTSI)
Conditions	Fibromyalgia (FM)
Enrollment	50 participants
Start Date	2026-06
Primary Completion	2027-05 (estimated)
Study Completion	2027-12 (estimated)
Updated on ClinicalTrials.gov	2026-06-12