Clinical Trial

CleaRRAflow: Isotonic Solution vs. TPA for IVH Clearance

Not Yet Recruiting Phase 4
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Summary
The study aims to investigate the effect of continuous tPA irrigation into the ventricles. Investigators believe it may be superior to the traditional every 8-hour bolus dosing and continuous isotonic solution irrigation alone. The protocol plans to analyze blood clearance and functional outcomes in the patients.
Trial Details
NCT Number NCT07643493
Lead Sponsor David Dornbos
Conditions Tissue Plasminogen Activator, Intraventricular Brain Hemorrhage
Enrollment 80 participants
Start Date 2026-06-01
Primary Completion 2028-05-31 (estimated)
Study Completion 2029-05-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-11