Diagnostic Performance of Serum Calprotectin in Acute Appendicitis

This prospective observational study evaluated the diagnostic performance of serum calprotectin in patients presenting with acute abdominal pain and suspected acute appendicitis. Patients with histopathologically confirmed acute appendicitis were compared with patients diagnosed with nonspecific abdominal pain. Serum calprotectin levels were analyzed and compared with conventional inflammatory markers and the Alvarado score to assess their diagnostic value in acute appendicitis.

NCT Number	NCT07643142
Lead Sponsor	Fatih Sultan Mehmet Training and Research Hospital
Conditions	Acute Appendicitis, Abdominal Pain
Enrollment	74 participants
Start Date	2015-12-13
Primary Completion	2016-04-19 (estimated)
Study Completion	2016-04-21 (estimated)
Updated on ClinicalTrials.gov	2026-06-11