The Effect of Esketamine on Cough Reflex During Tracheal Extubation in Patients Undergoing Non-inflatable Transoral Endoscopic Thyroid Surgery

This study intends to implement esketamine-assisted anesthesia in patients undergoing non-inflatable transoral endoscopic thyroidectomy through a prospective randomized controlled trial, in order to observe the effect of esketamine on coughing during extubation in thyroidectomy patients.

NCT Number	NCT07641673
Lead Sponsor	The Second Hospital of Anhui Medical University
Conditions	Thyroidectomy, Coughing Reflex
Enrollment	186 participants
Start Date	2026-06
Primary Completion	2027-05 (estimated)
Study Completion	2027-09 (estimated)
Updated on ClinicalTrials.gov	2026-06-11