Clinical Trial

MRI-Guided Accelerated cTBS for Generalized Anxiety Disorder

Not Yet Recruiting
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Summary
Generalized Anxiety Disorder (GAD) is a common psychiatric disorder associated with persistent anxiety, functional impairment, and incomplete response to existing treatments. Although transcranial magnetic stimulation (TMS) has shown therapeutic potential in anxiety disorders, conventional treatment schedules often require several weeks and may not provide sufficiently rapid symptom relief. This study aims to evaluate the efficacy and safety of precision-targeted accelerated continuous theta-burst stimulation (cTBS) guided by individualized functional connectivity between the intraparietal sulcus (IPS) and the amygdala in patients with GAD.
Trial Details
NCT Number NCT07640945
Lead Sponsor Central South University
Conditions Generalized Anxiety Disorder (GAD)
Enrollment 75 participants
Start Date 2026-06
Primary Completion 2027-01 (estimated)
Study Completion 2027-02 (estimated)
Updated on ClinicalTrials.gov 2026-06-11