Silicone Barrier Spray Versus Zinc Oxide Ointment for Incontinence-Associated Dermatitis

Incontinence-associated dermatitis (IAD) is a common skin condition among long-term care residents and is caused by prolonged exposure to urine or feces. IAD can lead to skin irritation, discomfort, impaired skin integrity, and an increased risk of secondary complications. Structured skin care, including cleansing and barrier protection, is recommended for the prevention and management of IAD. This randomized controlled trial evaluated the effectiveness of a silicone barrier spray compared with zinc oxide ointment as part of a structured skin care program for residents with mild IAD in a long-term care facility. Participants were randomly assigned to receive either silicone barrier spray or zinc oxide ointment following routine skin cleansing. Clinical severity of IAD and skin barrier function were assessed at baseline, Day 7, and Day 14 using standardized clinical and biophysical measurements, including IAD severity score, skin hydration, transepidermal water loss, skin pH, and skin temperature. The study aimed to determine whether silicone barrier spray provides comparable or improved outcomes compared with conventional zinc oxide ointment in the management of mild IAD.

NCT Number	NCT07637695
Lead Sponsor	Taoyuan Armed Forces General Hospital
Conditions	Incontinence-Associated Dermatitis, Dermatitis, Skin Barrier Dysfunction
Enrollment	40 participants
Start Date	2023-01-01
Primary Completion	2023-11-30 (estimated)
Study Completion	2023-11-30 (estimated)
Updated on ClinicalTrials.gov	2026-06-11