Clinical Trial

The Effects of Anesthesia on Postoperative Cognitive Functions in Patients Undergoing Sleeve Gastrectomy

Recruiting
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Summary
In this study, the investigators want to examine the effects of intravenous anesthetic drugs and gases on cognitive functions in the postoperative period in individuals who will undergo surgery for obesity. The investigators believe that the anesthesia method we apply with inhalation gases is also as reliable method as total intravenous anesthesia for postoperative cognitive functions in these patients who undergoe sleeve gastrectomy. The anesthesia method applied intravenously and with inahalational gases have been applied safely for many years. Comparisons between these two anesthesia technics in obese individuals and for postoperative cognitive dysfunctions are limited. Studies on the examination of cognitive functions in postoperative patients have gained momentum with the use of neuropsychiatric tests performed on patients who have undergone cardiac surgery and these tests have also been performed on individuals who have undergone non-cardiac surgery. And yet, similar declines in cognitive functions have been observed. For these reasons, the effects of surgery itself and anesthesia methods on cognitive functions have been studied up to date. In this study, the investigators plan to evaluate patients who will undergo obesity surgery in both anesthesia methods by the recovery times from anesthesia and the residual effects of anesthesia, and after awakening they plan to evaluate their cognitive functions with neuropsychiatric tests that will be performed at certain intervals.
Trial Details
NCT Number NCT07637357
Lead Sponsor Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Conditions POCD - Postoperative Cognitive Dysfunction, Recovery Time, Postoperative Neurocognitive Disorder, Postoperative Delirium, Bariatric Sleeve Gastrectomy, Delayed Neurocognitive Recovery, Total Intravenous Anesthesia, Inhalational Anesthesia +1 more
Enrollment 60 participants
Start Date 2025-09-30
Primary Completion 2026-04-30 (estimated)
Study Completion 2026-07-30 (estimated)
Updated on ClinicalTrials.gov 2026-06-09